Table 1. The expression of CENPK versus clinical features.

Clinicopathological parameters	Number of patients	Upregulation*	no up-regulation	X2	P
Age (years)
≥ 65years	16	11	5	0.51	> 0.05
< 65 years	81	48	33
Gender
Male	81	49	32	0.01	> 0.05
Female	17	11	6
HBV
HBV (+)	61	54	29	2.50	> 0.05
HBV (−)	6	6	8
Tumor size
≥ 3 cm	81	48	33	0.01	< 0.05
< 3 cm	9	6	3
Lymphatic metastasis
Present	3	1	2	0.19	> 0.05
Absent	102	64	38
AFP
≥ 400 ng/ml	36	26	10	4.38	< 0.05
< 400 ng/ml	41	20	21

*:up regulation of CENP-K was designed as ≥ 2(HCC/non-HCC).