Table 7. GO and KEGG enriched analysis for lncRNAs-related genes.
| Enriched analysis | Targets count | P value | FDR |
|---|---|---|---|
| AC079630.2 | |||
| GO terms (BP) | |||
| GO:0045165∼cell fate commitment | 5 | 2.00E-04 | 3.09E-01 |
| GO:0030318∼melanocyte differentiation | 4 | 2.58E-04 | 3.99E-01 |
| GO:0035556∼intracellular signal transduction | 9 | 4.00E-03 | 6.03E+00 |
| GO:0046777∼protein autophosphorylation | 6 | 4.69E-03 | 7.03E+00 |
| GO:0007275∼multicellular organism development | 10 | 5.70E-03 | 8.48E+00 |
| GO terms (CC) | |||
| GO:0016021∼integral component of membrane | 49 | 2.56E-03 | 3.09E+00 |
| GO:0005886∼plasma membrane | 41 | 3.28E-03 | 3.95E+00 |
| GO:0098794∼postsynapse | 3 | 8.82E-03 | 1.03E+01 |
| GO:0030054∼cell junction | 9 | 1.00E-02 | 1.16E+01 |
| GO:0005794∼Golgi apparatus | 13 | 1.01E-02 | 1.17E+01 |
| GO terms (MF) | |||
| GO:0004714∼transmembrane receptor protein tyrosine kinase activity | 4 | 1.97E-03 | 2.51E+00 |
| GO:0005154∼epidermal growth factor receptor binding | 3 | 1.76E-02 | 2.04E+01 |
| GO:0005524∼ATP binding | 17 | 3.52E-02 | 3.69E+01 |
| GO:0005088∼Ras guanyl-nucleotide exchange factor activity | 4 | 4.02E-02 | 4.10E+01 |
| GO:0030276∼clathrin binding | 3 | 4.59E-02 | 4.53E+01 |
| KEGG analysis | |||
| hsa05202:Transcriptional misregulation in cancer | 4 | 8.60E-02 | 6.40E+01 |
| CRNDE | |||
| GO terms (BP) | |||
| GO:0001755∼neural crest cell migration | 3 | 6.74E-03 | 9.02E+00 |
| GO:0007399∼nervous system development | 5 | 7.76E-03 | 1.03E+01 |
| GO:0042493∼response to drug | 4 | 5.04E-02 | 5.14E+01 |
| GO:0030206∼chondroitin sulfate biosynthetic process | 2 | 6.63E-02 | 6.16E+01 |
| GO:0048843∼negative regulation of axon extension involved in axon guidance | 2 | 6.89E-02 | 6.31E+01 |
| GO terms (CC) | |||
| GO:0005576∼extracellular region | 11 | 1.64E-02 | 1.61E+01 |
| GO:0005615∼extracellular space | 9 | 3.96E-02 | 3.49E+01 |
| GO:0043198∼dendritic shaft | 2 | 8.91E-02 | 6.29E+01 |
| GO terms (MF) | |||
| GO:0030215∼semaphorin receptor binding | 2 | 5.83E-02 | 5.05E+01 |
| GO:0045499∼chemorepellent activity | 2 | 6.81E-02 | 5.62E+01 |
| GO:0008146∼sulfotransferase activity | 2 | 9.21E-02 | 6.78E+01 |
| CTD-2171N6.1 | |||
| GO terms (BP) | |||
| GO:0030198∼extracellular matrix organization | 25 | 4.16E-24 | 6.26E-21 |
| GO:0030199∼collagen fibril organization | 12 | 8.10E-16 | 1.17E-12 |
| GO:0030574∼collagen catabolic process | 13 | 8.37E-15 | 1.25E-11 |
| GO:0001501∼skeletal system development | 12 | 1.52E-09 | 2.29E-06 |
| GO:0007155∼cell adhesion | 18 | 7.37E-09 | 1.11E-05 |
| GO terms (CC) | |||
| GO:0005578∼proteinaceous extracellular matrix | 25 | 7.15E-21 | 8.27E-18 |
| GO:0031012∼extracellular matrix | 24 | 1.23E-18 | 1.42E-15 |
| GO:0005576∼extracellular region | 43 | 7.28E-16 | 8.99E-13 |
| GO:0005615∼extracellular space | 35 | 2.50E-12 | 2.89E-09 |
| GO:0005581∼collagen trimer | 12 | 1.81E-11 | 2.09E-08 |
| GO terms (MF) | |||
| GO:0005201∼extracellular matrix structural constituent | 11 | 1.25E-11 | 1.55E-08 |
| GO:0004222∼metalloendopeptidase activity | 9 | 5.90E-07 | 7.33E-04 |
| GO:0005518∼collagen binding | 7 | 2.14E-06 | 2.65E-03 |
| GO:0005509∼calcium ion binding | 18 | 2.55E-06 | 3.17E-03 |
| GO:0008201∼heparin binding | 9 | 8.05E-06 | 9.99E-03 |
| KEGG analysis | |||
| hsa04512:ECM-receptor interaction | 13 | 3.51E-13 | 3.70E-10 |
| hsa04974:Protein digestion and absorption | 10 | 6.50E-09 | 6.85E-06 |
| hsa05146:Amoebiasis | 10 | 3.40E-08 | 3.59E-05 |
| hsa04510:Focal adhesion | 12 | 1.09E-07 | 1.15E-04 |
| hsa04151:PI3K-Akt signaling pathway | 12 | 1.75E-05 | 1.85E-02 |
GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; BP biological process; CC cellular component; MF molecular function.