Table 1. Association between CHD1L expression and various clinicopathological variables of patients with EC (Chi-square test).

Variable	All cases (n=191)	CHD1L protein expression		P value
		Low expression (n=105)	High expression (n=86)
Gender				0.068
Female	50	33	17
Male	141	72	69
Age at surgery				0.695
<60	125	70	55
≥60	66	35	31
Histology type				0.428
Ulcerating-type	68	33	35
Medullary-type	74	46	28
Fungating-type	38	20	18
Stricture-type	11	6	5
Clinical stages				0.003*
I	19	15	4
II	75	47	28
III	42	23	19
IV	55	20	35
Differentiation				0.590
Poor	36	18	18
Mediate	127	70	57
Well	27	17	10
Tumor location				0.656
Upper	27	14	13
Middle	140	80	60
Lower	23	11	12
Tumor size(cm)				0.612
<4	39	25	14
≥4	152	80	72
Lymph node metastasis				0.000*
None	90	27	63
<4	35	23	12
≥4	66	55	11

* P < 0.05 was considered significant.