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. 2017 Jun 16;8(43):74217–74232. doi: 10.18632/oncotarget.18540

Figure 7. Effect of APX-115 on mitochondrial biogenesis in STZ-induced diabetic mice.

Figure 7

(A) Paraffin-embedded kidney sections were stained with anti-PGC1α antibody (1:200; original magnification: 200×; scale bar: 100 μm). (B) Quantification of PGC1α stained positive area. mRNA expression levels of NRF1 (C) and TFAM (D) in kidney tissues were measured. Data are presented as means ± SE of 10–12 mice/group; *p < 0.05 vs. control, p < 0.05 vs. DM.