Figure 2. Knockdown of miR-146a inhibited OS cell proliferation and colony formation.
(A) qRT-PCR analysis of the expression levels of miR-146a in multiple OS cell lines. (B) qRT-PCR analysis of the knockdown efficiency of sh-miR-146a in U-2OS and Saos-2 cells. (C and D) The effects of miR-146a knockdown on cell proliferation of U-2OS and Saos-2 cells indicated by MTT assay. (E) The effects of miR-146a knockdown on cell colony formation of U-2OS and Saos-2 cells. * P<0.05, **P<0.01.