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. 2017 Aug 22;8(43):74320–74330. doi: 10.18632/oncotarget.20382

Figure 4. The mRNA expressions of inflammatory and oxidative markers in cerebral cortex by day 30 after chronic cerebral hypoperfusion (CHP) procedure (n = 6).

Figure 4

(A) mRNA expression of IL-1ß; (D, B) mRNA expression of tumor necrotic factor (TNF)-α, (C) The mRNA expression of monocyte chemoattractant protein (MCP)-1; D) The mRNA expression of NF-kB; (E) The mRNA expression of NOX-I; (F) The mRNA expression of NOX-II; The p < 0.05 indicates statistical significance between two groups. All statistical analyses using one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. SC = sham control; CHP = cerebral hypoperfusion; CHP-Mela = cerebral hypoperfusion with melatonin (10 mg/kg/day,ip); CHP-Mela-Luz= cerebral hypoperfusion with melatonin (10 mg/kg/day,ip) and luzindole (30 mg/kg,ip).