Table 1. Clinicopathological characteristics of the 506 patients with ESCC.

Characteristics		All patients			Patients with Stage I-II disease				Patients with DFS time≥30months				Patients with DFS time≥30months in stage I-II
		No.	%		No.		%		No.		%		No.		%
Total		506	100.0		301		100.0		259		100.0		201		100.0
Gender
Male		415	82.0		236		78.4		205		79.2		154		76.6
Female		91	18.0		65		21.6		54		20.8		47		23.4
Age
<60		215	42.5		121		40.2		117		45.2		89		44.3
≥60		291	57.5		180		59.8		142		54.8		112		55.7
Tumor site
Upper		29	5.7		20		6.6		15		5.8		14		7.0
Middle		238	47.0		158		52.5		124		47.9		106		52.7
Low		239	47.2		123		40.9		120		46.3		81		40.3
Differentiation
Well		21	4.2		15		5.0		13		5.0		12		6.0
Moderate		282	55.7		182		60.5		149		57.5		123		61.2
Poor		203	40.1		104		34.6		97		37.5		66		32.8
Clinical stage
I+II		301	59.5						201		77.6
III+IV		205	40.5						58		22.4
Invasive depth
I		111	21.9		106		35.2		76		29.3		73		36.3
II		224	44.3		126		41.9		104		40.2		84		41.8
III		171	33.8		69		22.9		79		30.5		44		21.9
Lymph node metastasis
No		262	51.8		250		83.1		178		68.7		177		88.1
Yes		244	48.2		51		16.9		81		31.3		24		11.9
Distant metastasis
No		447	88.3		275		91.4		249		96.1		196		97.5
Yes		59	11.7		26		8.6		10		3.9		5		2.5
Vessel involvement
No		396	78.3		268		89.0		209		80.7		177		88.1
Yes		110	21.7		33		11.0		50		19.3		24		11.9
Nerve involvement
No		323	63.8		226		75.1		183		70.7		152		75.6
Yes		183	36.2		75		24.9		76		29.3		49		24.4
Necrosis
No		353	69.8		225		74.8		185		71.4		152		75.6
Yes		153	30.2		76		25.2		74		28.6		49		24.4
Smoking
No		309	61.1		202		67.1		165		63.7		136		67.7
Yes		197	38.9		99		32.9		94		36.3		65		32.3
FGFR1 amplification
High		44	8.7		20		6.6		20		7.7		10		5.0
Low		18	3.6		8		2.7		9		3.5		7		3.5
Disomy		444	87.7		273		90.7		230		88.8		184		91.5

Invasive depth I, tumors had invaded to the mucous layer or submucosa; II, to the muscularis propria; III, to or beyond the adventitia.