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. 2017 Aug 24;8(43):74791–74805. doi: 10.18632/oncotarget.20422

Figure 7. In high glucose-treated H9c2 cardiomyoblasts, DATS markedly enhanced cellular AMPK/ACC signaling and AKT/GSK-3β/HIF-1α signaling, which was blunted by Compound C co-administration.

Figure 7

(A). representative blots; (B). p-AMPK/AMPK ratio; (C). p-ACC/ACC ratio; (D). p-AKT/AKT ratio; (E). p-GSK3β/GSK3β ratio; (F). HIF-1α expression. Data are expressed as mean ± SEM, n = 6 in each group; @@P < 0.01/@P < 0.05 vs the mannitol group, &&P < 0.01/&P < 0.05 vs the HG group, ^^P < 0.01/^P < 0.05 vs the HG+SIR group, ^^P < 0.01/^P < 0.05 vs the HG+SIR+DATS group. HG, high glucose; SIR, simulated ischemia-reperfusion; DATS, diallyl trisulfide; Com.C, Compound C.