Table 2. Multivariate analysis for overall survival.

Variable	HR	CI (95%)	P value
Depth of invasion	1.236	0.924–2.256	0.121
Lymph node metastasis	2.374	1.237–3.562	0.026
Distant metastasis	4.518	2.331–8.318	0.001
Tumor stage	5.231	3.169–7.573	0.000
Differentiation	1.252	0.726–1.842	0.535
IKKε expression	2.013	1.204–7.471	0.014