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. 2017 Sep 8;8(43):75308–75325. doi: 10.18632/oncotarget.20779

Figure 4. Metformin treatment prevented the loss of pericytes after HI injury.

Figure 4

(A) Representative micrographs showing immunofluorescence staining of PDGFR-β (green) in the hippocampus and cortex, and nucleus (blue) was labeled with DAPI. Scale bar = 50 μm. (B) Representative micrographs showing immunofluorescence staining of PDGFR-β (green) in the hippocampus and cortex, and nucleus (blue) was labeled with DAPI. Scale bar = 50 μm. (C, D) Representative western blots and quantification data of PDGFR-β and Desmin in the cortex (C) and hippocampus (D) at 24 h after HI injury. *P< 0.05, **P < 0.01 versus the sham group. #P< 0.05, ##P < 0.01 versus the HI group. Values represent the mean±SEM, Number of animals. n=5 for each group.