Table 2. Emerging therapies for the treatment of musculoskeletal consequences of androgen deprivation therapy.

Agents targeting bone	Agents targeting muscle
Chloride Channel Modulators	Androgen Receptor Modulators (SARM)
Anti-cathepsin K	GH Secretagogues
Anti-Integrins	PPAR-beta Modulators
Src inhibitors	Anti-Myostatin Antibodies
Androgen Receptor Modulators (SARM)	Myostatin Soluble Receptors
GLP2	Anti-Activin II Receptors
Inhibitor of gut serotonin	Angiotensin II Blockades
Anti-sclerostin	Beta-2 Receptor Agonists
Anti-Dickkopf	Anti-IL-6
Modulators of LRPs Pathway
Anti-activin	Anti-activin