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. Author manuscript; available in PMC: 2018 Oct 15.
Published in final edited form as: Arch Biochem Biophys. 2017 May 31;632:47–58. doi: 10.1016/j.abb.2017.05.017

Scheme 2.

Scheme 2

Chain initiation and elongation in isoprenoid biosynthesis. Note that both IPP and DMAPP are required in the initial condensation event (mediated by farnesyl pyrophosphate synthase). Thus, IDI enzymes serve an essential function for the growth and survival of most organisms.