FIGURE 4. CC3 is necessary but not sufficient for CCCP-1 function in C. elegans.
A, cccp-1 mutant animals have slow locomotion which is rescued by a single-copy transgene of GFP-tagged CCCP-1 cDNA expressed under the cccp-1 promoter. ***: p < 0.001, ns: p > 0.05, n=10 each. B, the slow locomotion of cccp-1 mutants is not rescued by expression of CC3 or other CCCP-1 fragments. **: p < 0.01, ns: p > 0.05 compared to cccp-1 mutant, n=10 each.