Skip to main content
. Author manuscript; available in PMC: 2018 Oct 15.
Published in final edited form as: Arch Biochem Biophys. 2017 Aug 9;632:158–174. doi: 10.1016/j.abb.2017.08.007

Figure 5. Reaction free energy profile along the reaction coordinate for EcPL CPD repair.

Figure 5

Shown are six major reaction steps (solid lines) with the structures of the excited flavin (orange) and all anionic thymine-related intermediates (blue) and products (green). The relative energy between each state is mainly determined from dynamics measurements. The intact back electron transfer (BET) (dashed grey) is slow and does not occur during repair because of the ultrafast C5–C5′ bond splitting. The reaction times are shown at the top of the diagram. LT, deactivation lifetime; FET, forward electron transfer; ER, electron return.