Table 1.
Parameters | Asthmatic patients | Disease controls |
---|---|---|
N | 50 | 35 |
Diagnoses | 50 patients with asthma; 47 patients with allergic rhinitis, 29 with chronic sinusitis, 42 with GERD, 3 with bronchiectasis and 5 with aspiration | 21 patients with chronic cough and concurrent allergic rhinitis & GERD, 6 patients with bronchiectasis, 7 with chronic aspiration and 1 with COPD |
Male/female | 28/22 | 19/16 |
Age | 53.1 ± 4 (52) | 54.3 ± 4 (53) |
FEV1 (%) | 71.4 ± 4 (72α)* [64–81β] | 89.4 ± 4 (89) [78–99] |
Reversibility (%) | 17.0 ± 6 (14)*[10–21] | 2.8 ± 0.6 (2) [0–6] |
PC20 (mg/ml) for methacholine | 2.7 ± 0.6 (2.3)*a [0.3–6] | 24.2 ± 0.8 (25) [20–25] |
Allergy skin test positivity | 44 | 24 |
Eosinophils/μL blood | 490 ± 88 (300)* [200–700] | 100 ± 21 (100) [0–200] |
Total IgE (KIU/L) | 277 ± 34 (177) [88–525] | 132 ± 72 (59) [32–266] |
BMI | 28.1 ± 2 (28) | 27.6 ± 1 (27) |
Asthma medications | systemic steroids: 10 patients Omalizumab: 13 ICS/LABA: 50 LTI: 19 SABA: 50 Tiotropium: 9 |
ICS/LABA: 7 SABA: 18 |
number in the parenthesis () indicates median;
numbers in [] indicate the range in the group.
P<0.05, Mann-Whitney U test;
performed with 35 patients