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Specific triggers are necessary for the secretion of renin into bloodstream by the kidneys. Renin hydrolyzes angiotensinogen to produce angiotensin I, which is further converted to angiotensin II by the angiotensin-converting enzyme. Angiotensin II acts to increase blood volume and maintain blood pressure, it also stimulates the release of aldosterone and antidiuretic hormone (ADH) to retain water and sodium.
