Figure 3.

Expression Pattern of Autophagy-Associated mRNAs and Their Corresponding lncRNAs during the LB Differentiation Process

(A and B) Log-log scatterplot and volcano plot show the differentially expressed lncRNAs between LBs and UiPSCs. (C) Heatmap was generated from a hierarchical cluster analysis to show the different expression profiling between LBs and UiPSCs. (D) Quantitative real-time PCR analysis of SH3GLB1 and its corresponding lncRNAs, including lncRNA p19101, lncRNA p38664_v4, lncRNA p13116, and lncRNA p4790. (E) Quantitative real-time PCR analysis of VMP1 and its corresponding lncRNAs, including lncRNA p13839 and lncRNA p36469_v4. (F) Quantitative real-time PCR analysis of LC3B and its corresponding lncRNAs, including lncRNA p35822_v4 and lncRNA ALB. (G) Quantitative real-time PCR analysis of WIPI1 and its corresponding lncRNA p34310_v4. The bar represents mean ± SEM (n = 3 independent experiments). a, p < 0.01 versus D0; A, p < 0.05 versus D0; b, p < 0.01 versus D7; B, p < 0.05 versus D7; c, p < 0.01 versus D14.