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. 2017 Oct 21;174(Suppl Suppl 1):S225–S271. doi: 10.1111/bph.13876
Nomenclature nucleotide binding oligomerization domain containing 1 nucleotide binding oligomerization domain containing 2 NLRC3 NLRC4 NLRC5 NLRX1 CIITA
HGNC, UniProt NOD1, Q9Y239 NOD2, Q9HC29 NLRC3, Q7RTR2 NLRC4, Q9NPP4 NLRC5, Q86WI3 NLRX1, Q86UT6 CIITA, P33076
Common abreviation NOD1 NOD2
Agonists meso‐DAP muramyl dipeptide
Comments NOD2 has also been reported to be activated by ssRNA [158] although this has not been widely reproduced. NLRC4 forms an inflammasome in conjunction with the NAIP proteins and responds to bacterial flagellin and type III secretion system rod proteins.