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. 2017 Oct 21;174(Suppl Suppl 1):S195–S207. doi: 10.1111/bph.13881
Nomenclature AQP0 AQP1 AQP2 AQP3 AQP4 AQP5
HGNC, UniProt MIP, P30301 AQP1, P29972 AQP2, P41181 AQP3, Q92482 AQP4, P55087 AQP5, P55064
Permeability water (low) water (high) water (high) water (high), glycerol water (high) water (high)
Endogenous activators cyclic GMP
Inhibitors Hg2+ Ag+, Hg2+, tetraethylammonium Hg2+ Hg2+ (also inhibited by acid pH) Hg2+
Comments AQP3 is also inhibited by acid pH AQP4 is inhibited by PKC activation