Nomenclature | AQP0 | AQP1 | AQP2 | AQP3 | AQP4 | AQP5 |
HGNC, UniProt | MIP, P30301 | AQP1, P29972 | AQP2, P41181 | AQP3, Q92482 | AQP4, P55087 | AQP5, P55064 |
Permeability | water (low) | water (high) | water (high) | water (high), glycerol | water (high) | water (high) |
Endogenous activators | – | cyclic GMP | – | – | – | – |
Inhibitors | Hg2+ | Ag+, Hg2+, tetraethylammonium | Hg2+ | Hg2+ (also inhibited by acid pH) | – | Hg2+ |
Comments | – | – | – | AQP3 is also inhibited by acid pH | AQP4 is inhibited by PKC activation | – |