Nomenclature | BMX non‐receptor tyrosine kinase | Bruton tyrosine kinase | TXK tyrosine kinase |
HGNC, UniProt | BMX, P51813 | BTK, Q06187 | TXK, P42681 |
EC number | 2.7.10.2 | 2.7.10.2 | 2.7.10.2 |
Common abreviation | Etk | Btk | TXK |
Inhibitors | compound 38 (pIC50 9.1) [300], ibrutinib (pIC50 9.1) [318], compound 31 (pIC50 8.7) [300] | ibrutinib (pIC50 9.3) [395], compound 31 (pIC50 8.4) [300], compound 38 (pIC50>8.4) [300] | – |
Selective inhibitors | BMX‐IN‐1 (pIC50 8.1) [307] | CGI1746 (pIC50 8.7) [120], CHMFL‐BTK‐11 (Irreversible inhibition) (pIC50 7.6) [576] | – |