Nomenclature	L‐Arginine decarboxylase	L‐Aromatic amino‐acid decarboxylase	Malonyl‐CoA decarboxylase	Ornithine decarboxylase	Phosphatidylserine decarboxylase	S‐Adenosylmethionine decarboxylase
HGNC, UniProt	AZIN2, Q96A70	DDC, P20711	MLYCD, O95822	ODC1, P11926	PISD, Q9UG56	AMD1, P17707
EC number	4.1.1.19	4.1.1.28: levodopa ‐>dopamine + CO2 5‐hydroxy‐L‐tryptophan ‐>5‐hydroxytryptamine + CO2 This enzyme also catalyses the following reaction:: L‐tryptophan ‐>tryptamine + CO2	4.1.1.9	4.1.1.17	4.1.1.65	4.1.1.50
Common abreviation	ADC	AADC	MLYCD	ODC	PSDC	SAMDC
Endogenous substrates	L‐arginine	levodopa, 5‐hydroxy‐L‐tryptophan, L‐tryptophan	malonyl‐CoA	L‐ornithine	phosphatidylserine	S‐adenosyl methionine
Products	agmatine [601]	5‐hydroxytryptamine, dopamine	acetyl CoA	putrescine	phosphatidylethanolamine	S‐adenosyl‐L‐ methioninamine
Cofactors	pyridoxal phosphate	pyridoxal phosphate	pyridoxal phosphate	pyridoxal phosphate	pyruvic acid	pyruvic acid
Selective inhibitors	–	3‐hydroxybenzylhydrazine, L‐α‐methyldopa, benserazide [108], carbidopa	–	APA (pIC50 7.5) [494], eflornithine (pK d 4.9) [422]	–	sardomozide (pIC50 8) [493]
Comments	The presence of a functional ADC activity in human tissues has been questioned [96].	AADC is a homodimer.	Inhibited by AMP‐activated protein kinase‐evoked phosphorylation [451]	The activity of ODC is regulated by the presence of an antizyme (ENSG00000104904) and an ODC antizyme inhibitor (ENSG00000155096).	S‐allylglycine is also an inhibitor of SAMDC [393].	s‐allylglycine is also an inhibitor of SAMDC [393].