| Nomenclature | phosphodiesterase 1A | phosphodiesterase 1B | phosphodiesterase 1C |
| HGNC, UniProt | PDE1A, P54750 | PDE1B, Q01064 | PDE1C, Q14123 |
| Common abreviation | PDE1A | PDE1B | PDE1C |
| Rank order of affinity | cyclic GMP>cyclic AMP | cyclic GMP>cyclic AMP | cyclic GMP = cyclic AMP |
| Endogenous activators | calmodulin (CALM1 CALM2 CALM3, P62158) | calmodulin (CALM1 CALM2 CALM3, P62158) | calmodulin (CALM1 CALM2 CALM3, P62158) |
| Inhibitors | crisaborole (pIC50 5.2) [8] | – | – |
| Selective inhibitors | SCH51866 (pIC50 7.2) [542], vinpocetine (pIC50 5.1) [319] | SCH51866 (pIC50 7.2) [542] | SCH51866 (pIC50 7.2) [542], vinpocetine (pIC50 4.3) [319] |
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