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. 2017 Oct 21;174(Suppl Suppl 1):S272–S359. doi: 10.1111/bph.13877
Nomenclature mPGES1 mPGES2 cPGES L‐PGDS
HGNC, UniProt PTGES, O14684 PTGES2, Q9H7Z7 PTGES3, Q15185 PTGDS, P41222
EC number 5.3.99.3: PGH2 = PGE2 5.3.99.3: PGH2 = PGE2 5.3.99.3: PGH2 = PGE2 5.3.99.2: PGH2 = PGD2
Cofactors glutathione dihydrolipoic acid
Comments Phosphorylated and activated by casein kinase 2 (CK2) [370]. Appears to regulate steroid hormone function by interaction with dimeric hsp90 [74, 253].