Nomenclature | mPGES1 | mPGES2 | cPGES | L‐PGDS |
HGNC, UniProt | PTGES, O14684 | PTGES2, Q9H7Z7 | PTGES3, Q15185 | PTGDS, P41222 |
EC number | 5.3.99.3: PGH2 = PGE2 | 5.3.99.3: PGH2 = PGE2 | 5.3.99.3: PGH2 = PGE2 | 5.3.99.2: PGH2 = PGD2 |
Cofactors | glutathione | dihydrolipoic acid | – | – |
Comments | – | – | Phosphorylated and activated by casein kinase 2 (CK2) [370]. Appears to regulate steroid hormone function by interaction with dimeric hsp90 [74, 253]. | – |