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. 2017 Oct 21;174(Suppl Suppl 1):S272–S359. doi: 10.1111/bph.13877
Nomenclature Leukotriene C4 synthase γ‐Glutamyltransferase Dipeptidase 1 Dipeptidase 2
HGNC, UniProt LTC4S, Q16873 GGCT, O75223 DPEP1, P16444 DPEP2, Q9H4A9
EC number 4.4.1.20: LTC4 = glutathione + LTA4 2.3.2.2: (5‐L‐glutamyl)‐peptide + an amino acid = a peptide + a 5‐L‐glutamyl amino acid LTC4 + H2O =>LTD4 + L‐glutamate 3.4.13.19: LTD4 + H2O = LTE4 + glycine 3.4.13.19: LTD4 + H2O = LTE4 + glycine
Inhibitors cilastatin (pK i 6) [189]