| Nomenclature | PAC 1 receptor | VPAC 1 receptor | VPAC 2 receptor |
| HGNC, UniProt | ADCYAP1R1, P41586 | VIPR1, P32241 | VIPR2, P41587 |
| Potency order of endogenous ligands | PACAP‐27 (ADCYAP1, P18509), PACAP‐38 (ADCYAP1, P18509) ≫VIP (VIP, P01282) | VIP (VIP, P01282), PACAP‐27 (ADCYAP1, P18509), PACAP‐38 (ADCYAP1, P18509) ≫GHRH (GHRH, P01286), PHI {Pig}, secretin (SCT, P09683) | VIP (VIP, P01282), PACAP‐38 (ADCYAP1, P18509), PACAP‐27 (ADCYAP1, P18509) >PHI {Pig} ≫GHRH (GHRH, P01286), secretin (SCT, P09683) |
| Selective agonists | maxadilan [446], maxadilan [446] | [Lys15,Arg16,Leu27]VIP‐(1‐7)/GRF‐(8‐27)‐NH 2 [1369], [Ala 11,22,28]VIP [1458] | Ro 25‐1553 [669, 930, 1369], Ro 25‐1392 [2144] |
| Selective antagonists | – | PG 97‐269 (pIC50 8.7) [668, 930] | – |
| Labelled ligands | [125 I]PACAP‐27 (Agonist) [1581] | [125 I]VIP (human, mouse, rat) (Agonist) [1458], [125 I]PACAP‐27 (Agonist) | [125 I]VIP (human, mouse, rat) (Agonist) [1458], [125 I]PACAP‐27 (Agonist) |
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