Nomenclature	5‐HT 5A receptor	5‐ht 5b receptor	5‐HT 6 receptor	5‐HT 7 receptor
HGNC, UniProt	HTR5A, P47898	HTR5BP, –	HTR6, P50406	HTR7, P34969
Selective agonists	–	–	WAY‐181187 [1734], E6801 (Partial agonist) [808], WAY‐208466 [139], EMD‐386088 [1291]	LP‐12 [1148], LP‐44 [1148], LP‐211 [1149] – Rat, AS‐19 [993], E55888 [212]
Antagonists	–	–	–	lurasidone (pK i 9.3) [868], pimozide (pK i 9.3) [1678] – Rat, vortioxetine (pK i 6.3) [96]
Selective antagonists	SB 699551 (pK i 8.2) [380]	–	SB399885 (pK i 9) [801], SB 271046 (pK i 8.9) [229], cerlapirdine (pK i 8.9) [371], SB357134 (pK i 8.5) [230], Ro 63‐0563 (pK i 7.9–8.4) [170, 1824]	SB269970 (pK i 8.6–8.9) [1949], SB656104 (pK i 8.7) [558], DR‐4004 (pK i 8.7) [647, 985], JNJ‐18038683 (pK i 8.2) [181], SB 258719 (Inverse agonist) (pK i 7.5) [1950]
Labelled ligands	[125 I]LSD (Agonist) [670], [3 H]5‐CT (Agonist) [670]	[125 I]LSD (Agonist) [1290] – Mouse, [3 H]5‐CT (Agonist) [2049] – Mouse	[11 C]GSK215083 (Antagonist) (pK i 9.8) [1531], [125 I]SB258585 (Selective Antagonist) (pK d 9) [801], [3 H]LSD (Agonist) [169], [3 H]Ro 63‐0563 (Antagonist) (pK d 8.3) [170], [3 H]5‐CT (Agonist)	[3 H]5‐CT (Agonist) [1949], [3 H]5‐HT (Agonist) [99, 1864], [3 H]SB269970 (Selective Antagonist) (pK d 8.9) [1949], [3 H]LSD (Agonist) [1864]