| Nomenclature | HCA 1 receptor | HCA 2 receptor | HCA 3 receptor |
| HGNC, UniProt | HCAR1, Q9BXC0 | HCAR2, Q8TDS4 | HCAR3, P49019 |
| Potency order of endogenous ligands | – | β ‐D‐hydroxybutyric acid>butyric acid | – |
| Endogenous agonists | L‐lactic acid [16, 266, 1190, 1854] | β ‐D‐hydroxybutyric acid [1912], butyric acid | 3‐hydroxyoctanoic acid [15] |
| Agonists | 3,5‐dihydroxybenzoic acid [1187] | SCH 900271 [1522], GSK256073 [1861] | – |
| Selective agonists | – | MK 6892 [1788], MK 1903 [166], nicotinic acid [1842, 1989, 2125], acipimox [1842, 2125], monomethylfumarate [1933] | compound 6o [1820], IBC 293 [1769] |
| Labelled ligands | – | [3 H]nicotinic acid (Agonist) [1842, 1989, 2125] | – |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.