Nomenclature	MC 1 receptor	MC 2 receptor	MC 3 receptor	MC 4 receptor	MC 5 receptor
HGNC, UniProt	MC1R, Q01726	MC2R, Q01718	MC3R, P41968	MC4R, P32245	MC5R, P33032
Potency order of endogenous ligands	α ‐MSH (POMC, P01189) >β ‐MSH (POMC, P01189) >ACTH (POMC, P01189), γ ‐MSH (POMC, P01189)	ACTH (POMC, P01189)	γ ‐MSH (POMC, P01189), β ‐MSH (POMC, P01189) >ACTH (POMC, P01189), α ‐MSH (POMC, P01189)	β ‐MSH (POMC, P01189) >α ‐MSH (POMC, P01189), ACTH (POMC, P01189) >γ ‐MSH (POMC, P01189)	α ‐MSH (POMC, P01189) >β ‐MSH (POMC, P01189) >ACTH (POMC, P01189) >γ ‐MSH (POMC, P01189)
Selective agonists	–	corticotropin zinc hydroxide	[D‐Trp 8]γ‐MSH [679]	THIQ [1760]	–
Antagonists	–	–	PG‐106 (pIC50 6.7) [680]	–	–
Selective antagonists	–	–	–	MBP10 (pIC50 10) [123], HS014 (pK i 8.5) [1738]	–
Labelled ligands	[125 I]NDP‐MSH (Agonist) [1037]	[125 I]ACTH‐(1‐24) (Agonist)	[125 I]NDP‐MSH (Agonist) [1037], [125 I]SHU9119 (Antagonist) [1457]	[125 I]SHU9119 (Antagonist) (pK d 9.2) [1457], [125 I]NDP‐MSH (Agonist) [1037, 1736]	[125 I]NDP‐MSH (Agonist) [1037]