| Nomenclature | MT 1 receptor | MT 2 receptor |
| HGNC, UniProt | MTNR1A, P48039 | MTNR1B, P49286 |
| Endogenous agonists | melatonin [70, 473, 475] | melatonin [70, 473, 475] |
| Agonists | ramelteon [954], agomelatine [70, 136] | agomelatine [70, 136], ramelteon [954, 1636] |
| Selective agonists | – | UCM1014 [1855], IIK7 [532, 1888], 5‐methoxy‐luzindole (Partial agonist) [475] |
| Selective antagonists | – | 4P‐PDOT (pK i 8.8–9.4) [70, 475, 476], K185 (pK i 9.3) [532, 1888], DH97 (pK i 8) [1939] |
| Labelled ligands | [125 I]SD6 (Agonist) [1138], 2‐[125 I]melatonin (Agonist) [70, 475], [3 H]melatonin (Agonist) [235] | [125 I]SD6 (Agonist) [1138], 2‐[125 I]melatonin (Agonist) [70, 475], [125 I]DIV880 (Agonist, Partial agonist) [1138], [3 H]melatonin (Agonist) [235] |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.