Table 1.
Summary of patients at low and high risk of SUDEP.
Characteristics | Low risk (n = 18) | High risk (n = 14) | p |
---|---|---|---|
Mean age at scan (years) ± SD | 30.0 ± 7.1 | 33.5 ± 9.1 | 0.332 |
Gender (M:F) | 9:9 | 7:7 | 1 |
Epilepsy lateralization (L:R) | 9:9 | 8:6 | 0.693 |
Mean age epilepsy onset (years) ± SD | 12.9 ± 9.5 | 12.4 ± 8.5 | 0.203 |
Mean epilepsy duration (years) ± SD | 17.6 ± 10.3 | 21.2 ± 12.3 | 0.068 |
>3 GTCS per year | 0 | 14 | <0.001 |
Mean number of GTCS per year | 0.3 ± 0.6 | 62 ± 58 | <0.001 |
Nocturnal seizures | 0 | 6 | 0.002 |
Hippocampal sclerosis | 7 | 9 | 0.161 |
Polytherapy | 13 | 12 | 0.367 |
Monotherapy | 5 | 2 | 0.367 |
Mean SUDEP risk (OR) score ± SD | 1.6 ± 1.7 | 19.2 ± 2.2 | <0.001 |
SUDEP, sudden death in epilepsy; L, left; R, right; GTCS, generalized tonic–clonic seizures; OR, odds ratio; AED, antiepileptic drug.