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. 2017 Oct 16;8:268. doi: 10.3389/fendo.2017.00268

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Copyright © 2017 Cui, Wang, Zhao, Zhang, Xu, Yang and Hao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The production of leukemia inhibitory factor (LIF) by RL95-2 after the stimulation with anandamide (AEA) and cannoibind receptor agonists. (A) The morphology of RL95-2 in the culture. (B) RL95-2 was stimulated by different concentrations of AEA (1, 5, and 10 µmol/L) for 24–72 h. (C) The production of LIF by RL95-2 was increased when cultured with low dose of AEA (1–5 µmol/L), whereas high dose of AEA (50 µmol/L) inhibited the LIF production. The experiments were repeated three times. The results were presented as mean. The significance of the variation was summarized in Table 5. *P < 0.05.