Chronic HIV infection is associated with alterations in mRNA levels of PPARγ, Nox1, Nox2, Nox4, and TGFβ1 in AMs. AMs were collected from HIV-uninfected control subjects (Control, n = 6) and from HIV-infected subjects (HIV, n = 22). mRNA levels of PPARγ (A), Nox1 (B), Nox2 (C), Nox4 (D), and TGFβ1
(E) were measured by quantitative real-time polymerase chain reaction (n = 28, in duplicate), normalized to 9s mRNA, and expressed as mean ± SEM, relative to control. *p < .05 versus control. AMs, alveolar macrophages; PPARγ, peroxisome proliferator-activated receptor gamma; TGFβ1, transforming growth factor beta-1.