FIG. 3.
Chronic HIV infection is associated with alterations in protein levels of PPARγ, Nox1, Nox2, Nox4, and TGFβ1 in AMs. AMs were collected from HIV-uninfected control subjects (Control, n = 6) and from HIV-infected subjects (HIV, n = 22). Protein levels of PPARγ (A), Nox1 (B), Nox2 (C), Nox4 (D), and TGFβ1 (E) were determined in AMs (n = 28, 10 fields per experimental condition) by using confocal fluorescence microscopy. Representative images are provided. Quantification of fluorescence values was normalized to DAPI nuclear stain and expressed as mean relative fluorescence units (RFU) per cell ± SEM, relative to control. *p < .05 versus control.