Table 2.

Effects of exercise and diet interventions on biomarker levels.

		Exercise Only		Diet Only			Diet & Exercise
	Baseline	18 months	Change	18 months	Change		18 months	Change
Description	Mean, SE (95% CI)	Mean, SE (95% CI)	Mean, SE (%)	Mean, SE (95% CI)	Mean, SE (%)	Effect Size	Mean, SE (95% CI)	Mean, SE (%)	Effect Size	P-value (18 months)
Log C1M Mean Result	11.56, 0.03 (11.51, 11.61)	11.48, 0.04 (11.40, 11.55)	−0.08, 0.04 (−0.66)	11.34, 0.04 (11.27, 11.41)	−0.21, 0.04 (−1.82)	−0.26	11.32, 0.04 (11.25, 11.39)	−0.23, 0.04 (−2.00)	−0.29	0.0035
Log C2M Mean Result	−0.82, 0.02 (−0.86, −0.78)	−0.82, 0.02 (−0.87, −0.78)	0.01, 0.02 (−0.84)	−0.83, 0.02 (−0.87, −0.78)	0.00, 0.02 (−0.35)	−0.01	−0.80, 0.02 (−0.84, −0.75)	0.03, 0.02 (−4.20)	0.07	0.5565
Log C3M Mean Result	10.70, 0.02 (10.66, 10.74)	10.64, 0.02 (10.59, 10.69)	−0.05, 0.02 (−0.49)	10.61, 0.03 (10.56, 10.66)	−0.09, 0.03 (−0.82)	−0.09	10.55, 0.02 (10.50, 10.60)	−0.15, 0.02 (−1.37)	−0.24	0.0208
Log CRPM Mean Result	9.84, 0.02 (9.80, 9.88)	9.73, 0.03 (9.68, 9.79)	−0.08, 0.03 (−0.84)	9.74, 0.03 (9.68, 9.79)	−0.08, 0.03 (−0.83)	0.00	9.71, 0.03 (9.65, 9.76)	−0.11, 0.03 (−1.12)	−0.06	0.6922

All 18 month means adjusted for baseline values, baseline BMI and gender. Effect size is based on comparison to the exercise only group.