Skip to main content
. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Osteoarthritis Cartilage. 2017 Jul 27;25(11):1822–1828. doi: 10.1016/j.joca.2017.07.015

Table 4.

Change in biomarker levels at 18 months in radiographic progressors compared to non-progressors.*

Variable Mean change Non-progressors N=180 Progressors N=76 P-value
Log C1M −0.21 (−0.28, −0.15) −0.21 (−0.30, −0.11) 0.91
Log C2M 0.03 (−0.01, 0.07) 0.03 (−0.02, 0.09) 0.82
Log C3M −0.13 (−0.17, −0.09) −0.09 (−0.15, −0.03) 0.29
Log CRPM −0.12 (−0.17, −0.07) −0.09 (−0.16, −0.02) 0.53
Log IL-6 −0.20 (−0.29, −0.12) −0.15 (−0.28, −0.02) 0.44
*

Tested using ANCOVA at 18 months, adjusted for baseline BMI, gender, randomization group, and baseline value of the outcome. Progressors defined as change in JSW < −0.7mm, while non-progressors had change in JSW > −0.35.