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Schematic overview of the mitochondrial stress response to burn trauma in skeletal muscle. ETC, electron transport chain; O2•−, Superoxide ion; •OH, hydroxyl ion; PRDX3, thioredoxin-dependent peroxide reductase; GPRX, glutathione peroxidase; HSP, heat shock protein; TOM, translocase of the outer membrane; TIM, translocase of the inner membrane; CHOP, C/enhancer-binding protein homologous protein; C/EBPβ, CCAAT/enhancer-binding protein β.
