Table 7.

Difference of AIx@HR75 between galcanezumab and placebo in change from predose by dose group on Day 14 after single subcutaneous injections to healthy subjects.

Dose group	Mean change	95% CI	P-value
Galcanezumab 1 mg–placebo	−4.301	−13.394, 4.791	0.3445
Galcanezumab 5 mg–placebo	−2.051	−10.605, 6.502	0.6303
Galcanezumab 25 mg–placebo	−1.605	−10.718, 7.508	0.7235
Galcanezumab 75 mg–placebo	−0.807	−8.979, 7.366	0.8428
Galcanezumab 200 mg–placebo	1.301	−7.274, 9.875	0.7606
Galcanezumab 600 mg–placebo	−0.375	−8.531, 7.781	0.9264

AIx@HR75, augmentation index at heart rate equal to 75; CI, confidence interval.