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. 2017 Oct 17;9:337. doi: 10.3389/fnagi.2017.00337

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Copyright © 2017 Oguchi, Ono, Tsuji, Shozawa, Somei, Inagaki, Mori, Yasumoto, Ono and Kiuchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of CSZ on Cu/Zn-Superoxide Dismutase (SOD) content, SOD activity in Aβ-stimulated SH-SY5Y cells. (A) Cu/Zn-SOD isozyme contents, (B) SOD activities in the cell lysate were determined. The effect of a MEK1/2 or p38 MAPK inhibitor was also examined. Values are expressed as mean + SEM. ^#Statistical significance compared vs. control cells (p < 0.05). ^##Statistical significance compared vs. control cells (p < 0.01). *Statistical significance compared vs. 2.5 μM Aβ-treated cells (p < 0.01). ^$Statistical significance compared vs. 2.5 μM Aβ + CSZ-treated cells (p < 0.01).