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Combined effect of the four miRNA binding site SNPs on GC risk.
| Combined effect of risk allelesa | Cases (%) | Controls (%) | χ 2 | P trend | OR (95% CI) |
|---|---|---|---|---|---|
| 0-1 | 328 (65.60) | 320 (64.00) | 1.00 | ||
| 2-3 | 161 (32.20) | 170 (34.00) | 0.34 | 0.56 | 0.92 (0.71, 1.20) |
| 4-5 | 11 (2.20) | 10 (2.00) | 0.03 | 0.87 | 1.07 (0.45, 2.56) |
| 0.18 | 0.67 | ||||
| Total | 500 (100) | 500 (100) |
GC: gastric cancer; SNP: single-nucleotide polymorphism; OR: odds ratio; CI: confidence interval. aThe risk alleles: rs3748067T, rs10889677C, rs1468488C, and rs887796G.
