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Synergistic effect between the PON1 rs854560 TT genotype and cigarette smoking (4 × 2 table).
| TT homozygosity | Cigarette smoking | CAD (n = 228) |
BD (n = 220) |
OR (95% CI) |
|---|---|---|---|---|
| 1 | 1 | 22 | 1 | 39.77 (5.26–300.70) |
| 1 | 0 | 11 | 17 | 1.17 0.52–2.62) |
| 0 | 1 | 117 | 61 | 3.46 (2.29–5.25) |
| 0 | 0 | 78 | 141 | 1 |
OR: odds ratio; CAD: coronary artery disease (patient group); BD: blood donor (control group).
