Table 4.
Synergy index (with 95% CI) for interactions between PON1 rs854560 TT genotype and traditional risk factors for CAD.
| Traditional risk factors | SIM (95% CI) | SI (95% CI) | RERI (95% CI) | AP (95% CI) |
|---|---|---|---|---|
| Male gender | 0.56 (0.12–2.57) | 0.30 (0.02–4.53) | −1.32 (−9.89–1.27) | −0.84 (−7.26–0.53) |
| Overweight/obesity | 2.67 (0.75–9.53) | 10.04 (0.06–1568.05) | 2.08 (−0.34–6.45) | 0.63 (−0.41–0.86) |
| TC/HDL 5 : 1 | 0.68 (0.19–2.46) | 1.16 (0.35–3.89) | 0.71 (−4.18–10.27) | 0.12 (−1.74–0.53) |
| TC (mmol/L) | 0.53 (0.15–1.87) | 0.86 (0.25–2.98) | −0.47 (−5.39–4.54) | −0.11 (−2.28–0.42) |
| LDL (mmol/L) | 0.34 (0.09–1.24) | 0.74 (0.25–2.22) | −1.56 (−9.40–5.04) | −0.29 (−2.66–0.36) |
| TG (mmol/L) | 0.50 (0.14–1.73) | 0.74 (0.21–2.60) | −0.92 (−4.98–3.72) | −0.26 (−2.63–0.32) |
| HDL (mmol/L) | 1.10 (0.28–4.36) | 1.77 (0.41–7.75) | 2.06 (−2.42–13.96) | 0.36 (−1.49–0.60) |