Table 2.
Group × Run MANOVAs and t-tests within groups and runs. NAcc: nucleus accumbens, ACC: anterior cingulate cortex, FMC: frontal medial cortex, OFC: orbitofrontal cortex.
| Anticipation phase | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| ROI | Main Effect of Run (F (p)) | Main Effect of Group (F (p)) | Group × Run (F (p)) | Runs t-test in MDD group (t (p)) | Runs t-test in Control Group (t (p)) | Group t-test during Run 1 (t (p)) | Group t-test during Run 2 (t (p)) |
| Left NAcc | .61 (0.44) | .05 (0.82) | 1.22 (0.27) | 1.78 (0.08) | −.17 (0.86) | −.25 (0.80) | .65 (0.51) |
| Right NAcc | .05 (0.83) | .20 (0.66) | 2.34 (0.13) | 1.73 (0.09) | −.67 (0.51) | −.22 (0.82) | 1.00 (0.32) |
| Left ACC | 1.30 (0.26) | .08 (0.78) | 1.63 (0.21) | 2.07 (0.05) | −.08 (0.94) | −.89 (0.38) | .34 (0.74) |
| Right ACC | 1.51 (0.22) | .01 (0.93) | 1.40 (0.24) | 2.19 (0.04) | .03 (0.98) | −.64 (0.52) | .43 (0.67) |
| Left caudate | .17 (0.68) | .23 (0.63) | 1.38 (0.25) | 1.54 (0.13) | −.39 (0.70) | −.05 (0.96) | .93 (0.36) |
| Right caudate | .26 (0.61) | .03 (0.86) | 1.70 (0.20) | 1.77 (0.09) | −.41 (0.69) | −.39 (0.70) | .80 (0.43) |
| Left FMC | .89 (0.35) | .28 (0.60) | 1.38 (0.25) | .19 (0.85) | −1.33 (0.20) | −.43 (0.67) | 1.05 (0.30) |
| Right FMC | .73 (0.40) | .08 (0.78) | 1.88 (0.18) | .46 (0.65) | −1.26 (0.22) | −.79 (0.43) | .98 (0.34) |
| Left OFC | .52 (0.47) | .14 (0.71) | 1.35 (0.25) | 1.48 (0.15) | −.30 (0.77) | −.35 (0.73) | .83 (0.41) |
| Right OFC | .21 (0.65) | .40 (0.53) | 1.05 (0.31) | 1.34 (0.19) | −.31 (0.76) | .05 (0.96) | .96 (0.34) |
| Left putamen | 1.99 (0.16) | .41 (0.52) | 1.03 (0.32) | 2.06 (0.05) | .24 (0.82) | −1.14 (0.26) | −.05 (0.96) |
| Right putamen | 1.33 (0.25) | .16 (0.70) | 1.16 (0.29) | 1.90 (0.07) | .05 (0.96) | −.91 (0.37) | .18 (0.86) |
| Left striatum | 1.36 (0.25) | .03 (0.87) | 1.53 (0.22) | 2.18 (0.04) | −.04 (0.97) | −.73 (0.47) | .39 (0.70) |
| Right striatum | .88 (0.35) | .02 (0.89) | 1.77 (0.19) | 2.10 (0.04) | −.21 (0.84) | −.71 (0.48) | .48 (0.64) |
| Outcome phase | |||||||
|
| |||||||
| ROI | Main Effect of Run (F (p)) | Main Effect of Group (F (p)) | Group × Run (F (p)) | Runs t-test in MDD group (t (p)) | Runs t-test in Control Group (t (p)) | Group t-test during Run 1 (t (p)) | Group t-test during Run 2 (t (p)) |
|
| |||||||
| Left NAcc | .58 (0.45) | .20 (0.66) | 2.20 (0.14) | 2.00 (0.05) | −.40 (0.69) | −.37 (0.72) | 1.23 (0.22) |
| Right NAcc | .02 (0.88) | .23 (0.64) | 4.14 (0.04) | 2.24 (0.03) | −.94 (0.36) | −.72 (0.48) | 1.55 (0.13) |
| Left ACC | 6.82 (0.01) | 1.02 (0.32) | 1.10 (0.30) | 3.06 (0.005) | .95 (0.36) | −1.41 (0.17) | −.30 (0.76) |
| Right ACC | 4.26 (0.04) | .04 (0.83) | 1.25 (0.27) | 2.64 (0.01) | .58 (0.57) | −.77 (0.45) | .40 (0.69) |
| Left caudate | .02 (0.89) | .48 (0.49) | 3.05 (0.09) | 1.45 (0.16) | −1.04 (0.31) | −.32 (0.75) | 1.59 (0.12) |
| Right caudate | .81 (0.37) | .24 (0.63) | 3.78 (0.06) | 2.72 (0.01) | −.55 (0.59) | −.54 (0.59) | 1.56 (0.13) |
| Left FMC | .36 (0.55) | .33 (0.57) | 1.58 (0.21) | 1.67 (0.10) | −.37 (0.72) | −1.25 (0.22) | .47 (0.64) |
| Right FMC | .42 (0.52) | .25 (0.62) | 3.71 (0.06) | 2.33 (0.03) | −.71 (0.49) | −1.66 (0.10) | 1.01 (0.32) |
| Left OFC | 1.33 (0.25) | .02 (0.90) | 2.49 (0.12) | 2.50 (0.02) | −.23 (0.82) | −.89 (0.38) | 1.00 (0.33) |
| Right OFC | .87 (0.35) | .13 (0.72) | .93 (0.34) | 1.70 (0.10) | −.02 (0.99) | −.23 (0.82) | .82 (0.42) |
| Left putamen | 2.79 (0.10) | .74 (0.39) | 1.29 (0.26) | 2.36 (0.02) | .32 (0.75) | −1.16 (0.26) | .08 (0.93) |
| Right putamen | 3.85 (0.06) | .30 (0.59) | 1.10 (0.30) | 2.50 (0.02) | .556 (0.58) | −.94 (0.35) | .23 (0.82) |
| Left striatum | 1.36 (0.25) | .03 (0.87) | 2.52 (0.12) | 2.37 (0.02) | −.25 (0.81) | −.91 (0.37) | .88 (0.39) |
| Right striatum | 2.70 (0.11) | .00 (0.98) | 2.69 (0.11) | 2.91 (0.01) | .00 (0.99) | −.81 (0.42) | .98 (0.33) |