Relationship between the retinal vascular plexuses and anatomic layers. (A) An illustration of the retinal vascular plexuses in red (labeled on right) hand drawn on top of a histological section of the human retina showing anatomic layers (labeled on left). The SVC supplies most of the the ganglion cell complex. The ICP straddles the IPL and INL. The DCP straddles the INL and OPL. (B) Cross-sectional projection-resolved optical coherence tomography angiograms (PR-OCTA) of a normal eye. The 6-mm section is taken 750 μm superior to the fovea. Flow signals (purple for retinal and red for choroidal blood flow) were overlaid on reflectance signal (gray scale). (C) PR-OCTA cross-section from a perimetric glaucomatous eye. Focal thinning of NFL and GCL could be visualized temporally in the glaucomatous eye (arrows), corresponding with the loss of capillaries in the SVC. Abbreviations: NFL = nerve fiber layer, GCL = ganglion cell layer, IPL = inner plexiform layer, GCC(NFL+GCL+IPL)=ganglion cell complex, INL = inner nuclear layer, OPL = outer plexiform layer, ONL = outer nuclear layer, SVC = superficial vascular complex (inner 80% of the GCC), ICP = intermediate capillary plexus (outer 20% of the GCC + inner 50% of INL), DCP = deep capillary plexus (outer 50% of INL + OPL).