Table 2.
Drugs acting at α7 nicotinic acetylcholine receptors
Drug class | Agent | Reference |
---|---|---|
Nonselective agonists | ACh Nicotine |
Albuquerque et al. (2009) |
Selective α7 agonists | Choline A-582941 AR-R1779 PHA-543613 PNU-282987 |
Albuquerque et
al. (2009) Millar et al. (2014) Papke et al., (2004) |
α7 Partial agonists | Encenicline GTS-21 |
Millar et al.
(2014) Meyer et al., (1998) Briggs et al., (1995) |
Selective α7 antagonists | Methyllycaconitine α-Conotoxin |
Millar et al. (2014) |
Positive allosteric modulators | ||
Type 1 | Galantamine LY-20087101 Ivermectin |
Williams et
al. (2011) Millar et al. (2014) |
Type 2 | PNU-120596 TQS A-867744 |
|
Type 1/Type 2 intermediate | JNJ1930942 |