Table 2.

CLL apoptosis in response to compound treatment

	Untreated	DMSO	Roli	BRL	Roli/BRL	BC54	P value (BC54 vs Roli/BRL)
Patient 1	46.6±1.37	47.5±1.12	76.7±0.76	52.5±0.78	78.7±0.86	87.3±0.76	0.0001
Patient 2	23.7±0.67	22.6±0.89	35.6±0.7	26.3±1.02	34.7±0.46	58.8±3.12	0.0001
Patient 3	4.9±0.47	4.9±0.31	20.3±2.18	5.1±0.72	27.2±0.83	39.8±1.79	0.0002

All compounds were tested at 20μM final concentrations. Each value represents the median and standard deviation of three independent assays (see Materials and Methods for details).