Skip to main content
. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Kidney Int. 2017 Jun 24;92(5):1178–1193. doi: 10.1016/j.kint.2017.03.037

Figure 11. Reduced KLF15 expression in human kidney biopsies with fibrosis.

Figure 11

(A) Previously reported gene expression arrays from Ju et al. 29 were utilized to examine KLF15 expression in RNA from microdissected tubulointerstitial compartments of kidney biopsies with arterial hypertension (HTN), diabetic kidney disease (DKD) as compared to healthy donor subjects (***p<0.01, Kruskal-Wallis test with Dunn’s post-test). (B) KLF15 expression was also examined in microdissected tubulointerstitial compartments of kidney biopsies with DKD as compared to healthy donor subjects from Woroniecka et al. 28 (**p<0.01, Mann-Whitney test). (C) Immunostaining for KLF15, α-SMA, and Hoechst were performed in kidney biopsies with early-stage DKD, late-stage DKD, and healthy donor nephrectomies. (D) ImageJ was used to quantify the intensity of expression in all three groups. (n=6, *p<0.05, **p<0.01, Kruskal-Wallis test with Dunn’s post-test).