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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Kidney Int. 2017 Jun 24;92(5):1178–1193. doi: 10.1016/j.kint.2017.03.037

Figure 9. Older Foxd1-Cre Klf15fl/fl mice exhibit an increase in fibrotic markers with renal dysfunction.

Figure 9

Foxd1-Cre Klf15fl/fl and Foxd1-Cre Klf15+/+ littermates were aged for 52 weeks and were subsequently sacrificed to evaluate for tubulointerstitial changes. Renal cortex was fixed for histology and stained for Hematoxylin and Eosin (H&E) and Periodic acid-Schiff (PAS). The representative images from 4 mice in each group are shown (X 20). (B) Serum urea nitrogen and (C) Serum creatinine were measured in age-matched mice. (n=6, *p<0.05, **p<0.01, Mann-Whitney test).