Figure S4.

Comparison of the Sc Ycg1–Brn1 Structure with Structures of Cohesin HEAT-Repeat Subunits, Related to Figures 2 and 3

Overview and structural alignments of Sc Ycg1–Brn1 with crystal structures of cohesin HEAT-repeat subunits Hs SA2–Scc1 (PDB: 4PK7), Ct Scc2 (PDB: 5T8V) and Lachancea thermotolerans (Lt) Pds5 (PDB: 5F0N). Alignments were generated by secondary structure matching using only C atoms from Sc Ycg1–Brn1 HEAT repeats 2 to 7 and structurally equivalent regions of the cohesin HEAT-repeat subunits.