Figure 4.

Inactivation of SOM Interneurons Did Not Change Speed Coding in Speed Cells

(A) Firing rate map, spike locations on trajectory, and normalized firing rate as a function of running speed for a representative MEC speed cell from mouse with hM4D-mCitrine expression in SOM interneurons. Data were collected before CNO, 30 min after, and 12 hr after.

(B) Cumulative frequency diagrams showing no significant change in speed-rate correlation of speed cells after SOM-interneuron inactivation (top). The mean firing rate of the speed cells showed a small decrease (bottom). See Figure S4 for absolute scores.

(C) Speed-rate relationship in layer II and III speed cells from animals with hM4D-mCitrine expression in MEC-SOM interneurons, plotted as in Figure 2C.

See also Figures S1, S2, and S4.