Figure 5.

Short term dynamics of auditory nerve synaptic inputs differs between radiate and planar cells. (A,B) Example eEPSC responses of a radiate cell (A) and a planar cell (B) to stimulus trains at different frequencies. Tick marks above the traces indicate the timing of the stimulus pulses. Dashed lines in the 200 Hz and 400 Hz trains mark the baseline of the EPSC responses. Color-coding applies to the entire figure (red: radiate; blue: planar). (C) Summary of the synaptic depression during stimulus trains at 50, 100, 200 and 400 Hz. EPSC_n/EPSC₁: all eEPSC sizes were normalized to the amplitude of the first eEPSC. Color traces in each panel showed recordings made under artificial cerebrospinal fluid (ACSF) containing either 2.5 mM Ca²⁺ and 1.5 mM Mg²⁺ (red and blue) or 1.2 mM Ca²⁺ and 0.8 mM Mg²⁺ (black and green). R: radiate neurons; P: planar neurons. (D) Summary of the average steady-state eEPSC amplitudes during the last 40 pulses of the stimulus trains in both cell types. Note that the plots are staggered to show the individual cells. (E) Summary of the average steady-state eEPSC charge during the last 40 pulses of the stimulus trains. Each symbol in (D,E) represents an individual neuron.